Research Groups

Dr Colleen Bamford

• Bio Sketch

Prof Colleen Bamford is originally from Port Elizabeth and studied medicine at the University of Cape Town (UCT). She worked as a medical officer chiefly in paediatrics before returning to UCT to specialise in medical microbiology. She worked as a consultant microbiologist for the NHLS at Tygerberg and Groote Schuur Hospitals between 2006 and 2017 before joining Pathcare in East London. 


• Research Interests

o Investigation and introduction of rapid diagnostic methods for laboratory use
o Antibiotic and diagnostic stewardship, including rational use of diagnostic tests at different levels of health care system to support antibiotic stewardship
o Carbapenem resistance


• Publications 

1. Jacobson, R, Minenza, N, Bamford, C, Nicol M. VIM-2 metallo-beta-lactamase-producing Pseudomonas aeruginosa causing an outbreak in South Africa. Journal of Antimicrobial Chemotherapy 2012; 67(7): 1797-1798

2. Manesen R, Bamford C, Smith M, Jacobson R, Moodley C, Williams S. Outbreak of carbapenem-resistant Klebsiella species in an academic hospital, Western Cape, May 2012. Communicable Diseases Surveillance Bulletin 2012; 10 (4): 82-86.

3. Bamford C, Bonorchis K, Ryan A, Hoffmann R, Naicker P, Maloba M, Nana T,  Zietsman I, Govind C.  Antimicrobial susceptibility patterns of Escherichia coli strains isolated from urine samples in South Africa from 2007-2011. South African Journal of Epidemiology and Infection 2012;27(2):46-52.

4. Mudau M, Jacobson R, Kuonza L, Morris V, Engelbrecht H, Minenza, N, Nicol M, Bamford C. Outbreak of Multi-Drug Resistant Pseudomonas Aeruginosa Bloodstream Infection in the Haematology Unit of a South African Academic Hospital. PLoS One 2013;8: e55985.

5. Boyles T, Bamford C, Bateman K, Blumberg L, Dramowski A, Karstaedt A, Korsman S, le Roux D, Maartens G, Madhi S, Naidoo R, Nuttall J, Reubenson G, Taljaard, J, Thomas J, van Zyl G, von Gottberg A, Whitelaw A, Mendelson M. Guidelines for the management of acute meningitis in children and adults in South Africa. South African Journal of Epidemiology and Infection 2013;28(1):5-15

6. Boyles T, Whitelaw A, Bamford C, Moodley M, Bonorchis K, Morris V, Rawoot N, Naicker V, Lusakiewicz I, Black J, Stead D,Lesosky M, Raubenheimer P, Dlamini S, Mendelson M. Antibiotic Stewardship Ward Rounds and a Dedicated Prescription Chart Reduce Antibiotic Consumption and Pharmacy Costs without Affecting Inpatient Mortality or Re-Admission Rates. PLOS ONE 2013;8(12):79747.

7. Kenyon C, Bonorchis K,Corcoran C,Meintjes G, Locketz M, Lehloenya R,Vismer H, Naicker P, Prozesky H, van Wyk M, Bamford C, du Plooy M, Imrie G, Dlamini S, Borman A, Colebunders R, Yansouni C, Mendelson M,Govender N. A Dimorphic Fungus Causing Disseminated Infection in South Africa. N Engl J Med 2013;369:1416-1424.

8. Visser-Kift E, Maartens G, Bamford C. Systematic review of the evidence for rational dosing of colistin. S Afr Med J 2014;104(3):183-186.

9. Lochan H, Bamford C, Eley B.  Blood cultures in sick children. S Afr Med J 2013;103(12):918-920.

10. Olga Perovic, Ashika Singh-Moodley, Adriano Dusé, Colleen Bamford, G Elliott, Khine Swe Swe-Han, Ranmini Kularatne, Warren Lowman, Andrew Whitelaw, Trusha Nana, Jeanette Wadula, Ruth Lekalakala, Adrienne Saif, Melony Fortuin De-Smit, Else Marais. National sentinel site surveillance for antimicrobial resistance in Klebsiella pneumoniae isolates in South Africa, 2010 – 2012. S Afr Med J 2014;104(8):563-568. 

11. W Lowman, C Bamford, C Govind, K Swe Swe Han, R Kularatne, M Senekal, A Brink, P Moodley, J Thomas, J Smit, O Perovic. The SASCM CRE-WG: consensus statement and working guidelines for the screening and laboratory detection of carbapenemase-producing Enterobacteriaceae. South Afr J Infect Dis 2014;29(1):5-11

12. Prevalence of gastrointestinal pathogenic bacteria in patients with diarrhoea attending Groote Schuur Hospital, South Africa. B Kullin, R Meggersee, J D’Alton, B Galvao, N Rajabally, A Whitelaw, C Bamford, SJ Reid, VR Abratt. S Afr Med J 2015;105(2):121-125.

13. Gqunta, K., Van Wyk, J., Ekermans, P., Bamford, C., Moodley, C., Govender, S. First report of an IMI-2 carbapenemase-producing Enterobacter asburiae clinical isolate in South Africa. South Afr J Infect Dis 2015;30(1):34-35

14. McKay R, Bamford C. Community- versus healthcare- acquired bloodstream infections at Groote Schuur Hospital, Cape Town. S Afr Med J 2015;105(5):363-369.

15. Raban MS, Bamford C, Joolay Y, Harrison MC. Impact of an educational intervention and clinical performance dashboard on neonatal bloodstream infections. S Afr Med J 2015;105(7):564-566.

16. Jacobson RK, Manesen MR, Moodley C, Smith M, Williams S, Nicol M, Bamford C. Molecular characterisation and epidemiological investigation of an outbreak of blaOXA-181 carbapenemase-producing isolates of Klebsiella pneumoniae in South Africa. S Afr Med J 2015; 105(12):1030-1035.

17. Perovic O, Iyaloo S, Kularatne R, Lowman W, Bosman N, Wadula J, Seetharam S, Duse A, Mbelle N, Bamford C, Dawood H, MahabeerY, Bhola P, Abrahams S, Singh-Moodley A. Prevalence and Trends of Staphylococcus aureus Bacteraemia in Hospitalized Patients in South Africa, 2010 to 2012: Laboratory-Based Surveillance Mapping of Antimicrobial Resistance and Molecular Epidemiology. PLoS ONE 2015;10(12): e0145429.

18. Smith AM, Naicker P, Bamford C, Shuping L, McCarthy KM, Sooka A, Smouse SL, Tau N, Keddy KH. 2016. Genome sequences for a cluster of human isolates of Listeria monocytogenes identified in South Africa in 2015. Genome Announc 2016; 4(2):e00200-16. doi:10.1128/genomeA.00200-16. 

19. Lochan H, Moodley C, Rip D, Bamfrod C, Hendricks M, Davidson A, Eley B.  Emergence of vancomycin-resistant enterococcus at tertiary paediatric hospital in South Africa.  S Afr Med J  2016;106(6): 562-566.

20. Wessels A, Bamford C, Lewis DA, Martini M, Wainwright, HC. Syphilitic lymphadenitis clinically and histologically mimicking lymphogranuloma venereum. S Afr Med J 2016;106(5):465-7

21. Wojno JM,  Moodley C, Pienaar J, Beylis N, Jacobsz L, Nicol MP, Rossouw J, Bamford C. Human brucellosis in South Africa: Public health and diagnostic pitfalls.  S Afr Med J 2016;106(9): 8823-885.

22. Malande O, du Plessis A, Rip D, Bamford C, Eley B. Invasive carbapenem-resistant Enterobacteriaceae infection at a paediatric hospital: A case series. S Afr Med J 2016;106(9): 877-882 

23. Buys H, Muloiwa R, Bamford C, Eley B. Klebsiella pneumoniae bloodstream infections at a South African children's hospital 2006-2011, a cross-sectional study. BMC Infectious Diseases 2016;16:570. 

24. Jermaine Khumalo, Mark Nicol , Diana Hardie, Rudzani Muloiwa, Phindile Mteshana, Colleen Bamford. Diagnostic accuracy of two multiplex realtime- polymerase chain reaction assays for the diagnosis of meningitis in children in a resource- limited setting. PLoS ONE 2017;12(3):e0173948. 

25. Anthony Smith, Shannon Smouse; Nomsa Tau; Colleen Bamford; Vineshree Moodley; Charlene Jacobs; Kerrigan McCarthy; Adre Lourens; Karen Keddy. Laboratory-acquired infections of Salmonella enterica serotype Typhi in South Africa: phenotypic and genotypic analysis of isolates. BMC Infectious Diseases 2017 Sep 29;17(1):656.

26. Harsha Lochan, Vashini Pillay, Colleen Bamford, James Nuttall, Brian Eley.  Bloodstream infections at a tertiary level paediatric hospital in South Africa. BMC Infectious Diseases (2017) 17:750

27. Opperman C, Bamford C. Co-infection with Streptococcus pneumoniae and Listeria monocytogenes in an immunocompromised patient. S Afr Med J 2018;108(5):386-388.

28. Nicola Steinhaus, Mohammed Al-talib, Prudence Ive, Tom Boyles, Colleen Bamford, Mary-Ann Davies, Marc Mendelson, Sean Wasserman. The Management and Outcomes of Staphylococcus aureus Bacteraemia at a South African Referral Hospital: A Prospective Observational Study. International Journal of Infectious Diseases. 2018; 73:78-84

29. Tisungane Mvalo, Brian Eley, Colleen Bamford, Christopher Stanley, Maganizo Chagomerana, Marc Hendricks, Ann Van Eyssen, Alan Davidson. Bloodstream infections in Oncology patients at Red Cross War Memorial Children‘s Hospital, Cape Town from 2012 to 2014. International Journal of Infectious Diseases. 2018; 77: 40-47.  

30. Andrea Young, Mark Nicol, Clinton Moodley, Colleen Bamford. The accuracy of extended-spectrum beta-lactamase detection in Escherichia coli and Klebsiella pneumoniae in South African laboratories using the Vitek 2 Gram-negative susceptibility card AST-N255. S Afr J Infect Dis. 2019;34(1), a114. 

31. Bamford C, Milligan P, Kaliski S. Dangers of Clostridium perfringens food poisoning in psychiatric patients. South African Journal of Psychiatry. 25:a1339

32. Malande O, Nuttall J, Pillay V, Bamford C, Eley B. A ten year review of ESBL and non-ESBL Escherichia coli bloodstream infections among children at a tertiary referral hospital in South Africa. PLOS ONE.  2019; 14(9): e222675

33. Carbapenem-resistant enterobacteriacease in patients with bacteraemia at tertiary hospitals in South Africa, 2015 to 2018.  Eur J Clin Microbiol Infect Dis.  2020; 39(7)1287-1294